作者
Lauren M Schwartz, Philip E Castle, Stephen Follansbee, Sylvia Borgonovo, Barbara Fetterman, Diane Tokugawa, Thomas S Lorey, Vikrant V Sahasrabuddhe, Patricia Luhn, Julia C Gage, Teresa M Darragh, Nicolas Wentzensen
发表日期
2013/12/1
期刊
The Journal of infectious diseases
卷号
208
期号
11
页码范围
1768-1775
出版商
Oxford University Press
简介
Background. Carcinogenic human papillomaviruses (HPVs) cause a large proportion of anal cancers. Human immunodeficiency virus (HIV)–infected men who have sex with men (MSM) are at increased risk of HPV infection and anal cancer compared with HIV-negative men. We evaluated risk factors for HPV infection and anal precancer in a population of HIV-infected MSM.
Methods. Our study included 305 MSM at an HIV/AIDS clinic in the Kaiser Permanente Northern California Health Maintenance Organization. Logistic regression was used to estimate associations of risk factors comparing men without anal HPV infection; men with anal HPV infection, but no precancer; and men with anal precancer.
Results. Low CD4 count (<350 cells/mm3) and previous chlamydia infection were associated with an increased risk of carcinogenic HPV …
学术搜索中的文章
LM Schwartz, PE Castle, S Follansbee, S Borgonovo… - The Journal of infectious diseases, 2013