作者
Lauren M Schwartz, K Zaman, Md Yunus, Ahasan-ul H Basunia, Abu Syed Golam Faruque, Tahmeed Ahmed, Mustafizur Rahman, Jonathan D Sugimoto, M Elizabeth Halloran, Ali Rowhani-Rahbar, Kathleen M Neuzil, John C Victor
发表日期
2019/11/27
期刊
Clinical Infectious Diseases
卷号
69
期号
12
页码范围
2059-2070
出版商
Oxford University Press
简介
Background
Following the conclusion of a human rotavirus vaccine (HRV) cluster-randomized, controlled trial (CRT) in Matlab, Bangladesh, HRV was included in Matlab’s routine immunization program. We describe the population-level impact of programmatic rotavirus vaccination in Bangladesh in children <2 years of age.
Methods
Interrupted time series were used to estimate the impact of HRV introduction. We used diarrheal surveillance collected between 2000 and 2014 within the 2 service delivery areas (International Centre for Diarrhoeal Disease Research, Bangladesh [icddr,b] service area [ISA] and government service area [GSA]) of the Matlab Health and Demographic Surveillance System, administered by icddr,b. Age group–specific incidence rates were calculated for both rotavirus-positive (RV+) and rotavirus-negative (RV–) diarrhea diagnoses of any severity …
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