作者
Douglas Krakower, Kevin M Maloney, Victoria E Powell, Ken Levine, Chris Grasso, Kathy Melbourne, Julia L Marcus, Kenneth H Mayer
发表日期
2019/2
期刊
Journal of the International AIDS Society
卷号
22
期号
2
页码范围
e25250
简介
Introduction
Discontinuations of HIV preexposure prophylaxis (PrEP) by at‐risk individuals could decrease the effectiveness of PrEP. Our objective was to characterize patterns of, reasons for, and clinical outcomes associated with PrEP discontinuations in primary care.
Methods
We conducted medical chart reviews for patients prescribed PrEP during 2011 to 2014 at a Boston community health centre specializing in healthcare for sexual and gender minorities. Patients were followed through 2015. We characterized patients’ sociodemographics, relationship status, behavioural health conditions, patterns of and reasons for PrEP discontinuations, and HIV seroconversions. Cox proportional hazards models were used to assess patient factors associated with PrEP discontinuations.
Results
Of the 663 patients prescribed PrEP, the median age was 33 years, 96% were men who have sex with men (MSM) and 73 …
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D Krakower, KM Maloney, VE Powell, K Levine… - Journal of the International AIDS Society, 2019