作者
Ibrahim F Shatat, Katherine D Freeman, Patricia M Vuguin, Joan R Dimartino-Nardi, Joseph T Flynn
发表日期
2009/6
期刊
Pediatric research
卷号
65
期号
6
页码范围
691-695
出版商
Nature Publishing Group
简介
Obesity is associated with elevated blood pressure (BP), insulin resistance, and altered plasma adiponectin levels; the relationship between the biochemical features of obesity and 24-h ambulatory blood pressure (24-h ABP) parameters in adolescents remains unknown. Anthropometric measurements and 24-h ABP monitoring were obtained on 41 obese adolescents with and without type 2 diabetes mellitus (T2DM). Serum adiponectin, high sensitivity C-reactive protein (hs-CRP), lipid profile, insulin, fasting glucose, liver enzymes, Hb A1c (HbA1c), and two random urine samples were obtained for creatinine and microalbumin measurements. The determinants of 24-h systolic (SBP) and diastolic (DBP) BP were examined using multivariate linear regression models with BP parameters as outcome variables. Forty-one obese adolescents were studied. Adiponectin levels were reduced and hs-CRP levels were …
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IF Shatat, KD Freeman, PM Vuguin, JR Dimartino-Nardi… - Pediatric research, 2009