作者
Khalid Halahleh, Robert Peter Gale, Waleed Da’na, Mohammad Ma’koseh, Salwa Saadeh, Waseem Alan, Dana Yousef, Rozan Al-Far, Isra Muradi, Husam Abujazar, Hasan Hashem
发表日期
2021/1
期刊
Bone Marrow Transplantation
卷号
56
期号
1
页码范围
4-6
出版商
Nature Publishing Group UK
简介
Poor graft function is a serious complication of allogeneic hematopoietic cell transplantation. The diagnosis is based on presence of≥ 2 of the following:(1) haemoglobin concentration< 100g/L;(2) neutrophils< 1.0× 10E+ 9/L; and (3) platelets< 30× 10E+ 9/L) on day≥ 30 post transplant [1]. Other criteria include receiving RBC and platelet requiring transfusions, decreased bone marrow cellularity, complete donor chimerism and no graft-versus-host disease (GvHD) or relapse. Late failure of platelet recovery is defined as a decrease of platelet to< 20× 10E+ 9/L for 7 consecutive days or receiving platelet transfusions after achieving sustained platelets≥ 50× 10E+ 9/L without platelet transfusions for 7 consecutive days post transplant. Poor graft function is reported in 5–25% of allotransplant recipients and is associated with increased morbidity and mortality [1]. Current therapies including RBC and platelet transfusions …
引用总数
20212022202320243741
学术搜索中的文章
K Halahleh, RP Gale, W Da'na, M Ma'koseh, S Saadeh… - Bone Marrow Transplantation, 2021