作者
Aaron Reuben, Avshalom Caspi, Daniel W Belsky, Jonathan Broadbent, Honalee Harrington, Karen Sugden, Renate M Houts, Sandhya Ramrakha, Richie Poulton, Terrie E Moffitt
发表日期
2017/3/28
期刊
Jama
卷号
317
期号
12
页码范围
1244-1251
出版商
American Medical Association
简介
Importance
Many children in the United States and around the world are exposed to lead, a developmental neurotoxin. The long-term cognitive and socioeconomic consequences of lead exposure are uncertain.
Objective
To test the hypothesis that childhood lead exposure is associated with cognitive function and socioeconomic status in adulthood and with changes in IQ and socioeconomic mobility between childhood and midlife.
Design, Setting, and Participants
A prospective cohort study based on a population-representative 1972-1973 birth cohort from New Zealand; the Dunedin Multidisciplinary Health and Development Study observed participants to age 38 years (until December 2012).
Exposures
Childhood lead exposure ascertained as blood lead levels measured at age 11 years. High blood lead levels were observed among children from all socioeconomic status levels in this cohort.
Main Outcomes and …
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A Reuben, A Caspi, DW Belsky, J Broadbent… - Jama, 2017