作者
Sofia Doubrovinskaia, Christoph M Mooshage, Corinna Seliger, Hanns‐Martin Lorenz, Simon Nagel, Pascal Lehnert, Jan Purrucker, Brigitte Wildemann, Martin Bendszus, Wolfgang Wick, Silvia Schönenberger, Leon D Kaulen
发表日期
2023/2
期刊
European journal of neurology
卷号
30
期号
2
页码范围
463-473
简介
Background and purpose
Population‐based studies suggest severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) vaccines may trigger neurological autoimmunity including immune‐mediated thrombotic thrombocytopenia. Long‐term characterization of cases is warranted to facilitate patient care and inform vaccine‐hesitant individuals.
Methods
In this single‐center prospective case study with a median follow‐up of 387 days long‐term clinical, laboratory and imaging characteristics of patients with neurological autoimmunity diagnosed in temporal association (≤6 weeks) with SARS‐CoV‐2 vaccinations are reported.
Results
Follow‐up data were available for 20 cases (central nervous system demyelinating diseases n = 8, inflammatory peripheral neuropathies n = 4, vaccine‐induced immune thrombotic thrombocytopenia n = 3, myositis n = 2, myasthenia n = 1, limbic encephalitis n = 1, giant cell …
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S Doubrovinskaia, CM Mooshage, C Seliger… - European journal of neurology, 2023