作者
Chandini Raina MacIntyre, Yi Zhang, Abrar Ahmad Chughtai, Holly Seale, Daitao Zhang, Yanhui Chu, Haiyan Zhang, Bayzidur Rahman, Quanyi Wang
发表日期
2016/12/1
期刊
BMJ open
卷号
6
期号
12
页码范围
e012330
出版商
British Medical Journal Publishing Group
简介
Rationale
Medical masks are commonly used by sick individuals with influenza-like illness (ILI) to prevent spread of infections to others, but clinical efficacy data are absent.
Objective
Determine whether medical mask use by sick individuals with ILI protects well contacts from related respiratory infections.
Setting
6 major hospitals in 2 districts of Beijing, China.
Design
Cluster randomised controlled trial.
Participants
245 index cases with ILI.
Intervention
Index cases with ILI were randomly allocated to medical mask (n=123) and control arms (n=122). Since 43 index cases in the control arm also used a mask during the study period, an as-treated post hoc analysis was performed by comparing outcomes among household members of index cases who used a mask (mask group) with household members of index cases who did not use a mask (no-mask group).
Main outcome measure
Primary outcomes measured in …
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CR MacIntyre, Y Zhang, AA Chughtai, H Seale… - BMJ open, 2016