作者
Siva S Panda, M Chand, R Sakhuja, SC Jain
发表日期
2013/12/1
来源
Current medicinal chemistry
卷号
20
期号
36
页码范围
4481-4507
出版商
Bentham Science Publishers
简介
Xanthones (dibenzo-γ-pyrones) constitutes an important class of oxygenated heterocycles and occur as secondary metabolites in plants and microorganisms. They are known for various biological activities such as antioxidant, monoamine oxidase inhibitor, antihypertensive, hepatoprotective, antithrombotic, antifungal and anticancer. The tricyclic scaffold as well as the nature and/or position of the substituents present on it play an important role in displaying various biological activities. The unique structural scaffold and medicinal importance of xanthones have therefore attracted many Scientists in the past, to isolate or synthesize xanthones or their analogs as potential drug candidates. It would not be wrong to call them as close cousins to the polyphenol family that are known to possess strong antioxidant effects on the nervous system. The main two sources of xanthones are: Isolation from natural resources or …
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学术搜索中的文章
SS Panda, M Chand, R Sakhuja, SC Jain - Current medicinal chemistry, 2013