作者
Amirmohammad Khalaji, Amir Hossein Behnoush, Behrad Saeedian, Shaghayegh Khanmohammadi, Zahra Shokri Varniab, Soheil Peiman
发表日期
2023/5/16
来源
Diabetology & Metabolic Syndrome
卷号
15
期号
1
页码范围
102
出版商
BioMed Central
简介
Background
Diabetes is one of the chronic conditions with a high burden all around the world. Macrovascular and microvascular involvement are among the common mechanisms by which diabetes can impact patients’ lives. Endocan as an inflammatory endothelial biomarker has been shown to increase in several communicable and non-communicable diseases. Herein, we aim to investigate the role of endocan as a biomarker in diabetes as a systematic review and meta-analysis.
Methods
International databases, including PubMed, Web of Science, Scopus, and Embase were searched for relevant studies assessing blood endocan in diabetic patients. Estimation of the standardized mean difference (SMD) and 95% confidence interval (CI) for comparison of circulating endocan levels between diabetic patients and non-diabetic controls were conducted through random-effect meta-analysis.
Results
Totally, 24 studies …
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A Khalaji, AH Behnoush, B Saeedian… - Diabetology & Metabolic Syndrome, 2023