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Plants are an important source of chemical constituents, which have potential as functional food and therapeutic agents. The ethanolic extract of Phyllanthus emblica leaves exhibited inhibition (61.12%) against α-amylase at pH 7 and temperature 40 C. The extract acts as a non-competitive inhibitor and reduces turnover number (Kcat) and catalytic efficiency (Kcat/Km). It contains phenol and vitamin C content, 117 and 5.12 mg g-1 respectively. Antioxidant activity of leave extract (600 µg ml-1) is equivalent to the 800 µg ml-1 strength of ascorbic acid. The extract has antibacterial effectiveness against bacteria strains E. coli and S. aureus test organisms.