作者
Jean-Paul Carrera, Karoun H Bagamian, Amelia P Travassos Da Rosa, Eryu Wang, Davis Beltran, Nathan D Gundaker, Blas Armien, Gianfranco Arroyo, Nestor Sosa, Juan Miguel Pascale, Anayansi Valderrama, Robert B Tesh, Amy Y Vittor, Scott C Weaver
发表日期
2018/6
期刊
The American journal of tropical medicine and hygiene
卷号
98
期号
6
页码范围
1798
出版商
The American Society of Tropical Medicine and Hygiene
简介
Members of the genera Alphavirus (family Togaviridae) and Flavivirus (family Flaviridae) are important zoonotic human and equine etiologic agents of neurologic diseases in the New World. In 2010, an outbreak of Madariaga virus (MADV; formerly eastern equine encephalitis virus) and Venezuelan equine encephalitis virus (VEEV) infections was reported in eastern Panamá. We further characterized the epidemiology of the outbreak by studying household contacts of confirmed human cases and of equine cases with neurological disease signs. Serum samples were screened using a hemagglutination inhibition test, and human results were confirmed using plaque reduction neutralization tests. A generalized linear model was used to evaluate the human MADV and VEEV seroprevalence ratios by age (in tercile) and gender. Overall, antibody prevalence for human MADV infection was 19.4%, VEEV 33.3%, and …
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JP Carrera, KH Bagamian, APT Da Rosa, E Wang… - The American journal of tropical medicine and hygiene, 2018