作者
Umberto Benedetto, Giovanni Melina, Johanna JM Takkenberg, Antonino Roscitano, Emiliano Angeloni, Riccardo Sinatra
发表日期
2011/6/15
来源
Heart
卷号
97
期号
12
页码范围
955-958
出版商
BMJ Publishing Group Ltd
简介
Context
Surgical treatment of aortic root aneurysm in Marfan syndrome (MFS) patients.
Objective
To compare results of total root replacement versus valve-sparing aortic root replacement in MFS patients.
Data Sources
PubMed, Embase and Cochrane library were searched from January 1966 until February 2010 looking for papers reporting on aortic root operations in MFS patients. 530 studies were retrieved.
Study Selection
Finally, 11 publications were enrolled. Inclusion criteria were observational studies reporting valve-related morbidity and mortality after total root replacement (TTR) and/or valve-sparing root replacement (VSRR) in patients with MFS and study size n≥30, reflecting the centre's experience.
Data Extraction
Data obtained from papers reporting both TRR and VSRR cohorts were analysed separately. In case of multiple publications, the most recent and complete report was selected. If the total number …
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