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This paper focuses on the cross-layer issue of joint multiuser detection and resource allocation for energy efficiency in wireless code-division multiple-access (CDMA) networks. In particular, assuming that a linear multiuser detector is adopted in the uplink receiver, the situation considered is that in which each terminal is allowed to vary its transmit power, spreading code, and uplink receiver in order to maximize its own utility, which is defined as the ratio of data throughput to transmit power. Applying a game-theoretic formulation, a non-cooperative game for utility maximization is formulated, and it is proved that a unique Nash equilibrium exists, which, under certain conditions, is also Pareto-optimal. Theoretical results concerning the relationship between the problems of signal-to-interference-plus noise ratio (SINR) maximization and mean-square error (MSE) minimization are given, and, by applying the tools of …