作者
Alireza Neshani, Hamid Sedighian, Seyed Ali Mirhosseini, Kiarash Ghazvini, Hosna Zare, Abolfazl Jahangiri
发表日期
2020/9/1
来源
Microbial pathogenesis
卷号
146
页码范围
104238
出版商
Academic Press
简介
Background
With the increasing rate of antibiotic resistance in Acinetobacter, the World Health Organization introduced the carbapenem-resistant isolates in the priority pathogens list for which innovative new treatments are urgently needed. Antimicrobial peptides (AMPs) are one of the antimicrobial agents with high potential to produce new anti-Acinetobacter drugs. This review aims to summarize recent advances and compare AMPs with anti-Acinetobacter baumannii activity.
Methods
Active AMPs against Acinetobacter were considered, and essential features, including structure, mechanism of action, anti-A. baumannii potent, and other prominent characteristics, were investigated and compared to each other. In this regard, the Google Scholar search engine and databases of PubMed, Scopus, and Web of Science were used.
Results
Forty-six anti-Acinetobacter peptides were identified and classified into ten groups …
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A Neshani, H Sedighian, SA Mirhosseini, K Ghazvini… - Microbial pathogenesis, 2020