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Drought is one of the most significant natural phenomena affecting different aspects of human life and the environment. Due to water scarcity, prediction of water quality reduction is very crucial for urban and rural communities. This study contributes by applying artificial neural network and modified fuzzy clustering techniques to estimate the drops in potential drinking water quality in the GIS environment. In this research, the probability of occurrence of adverse annual changes in the water quality of drinking water is estimated. The model was tested using real instances of the southeast aquifers, the regions of the central parts of the IRAN and especially the significant portions of the aquifers of the east area. To validate the model, the data adequacy test and the standardization of the drought index are used. The results of the lowest available water quality and the highest drought using ANNs show that the qualitative …