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Methods: 18 patients (mean age= 53±6.07) and body mass index (26/1±2.1 kg/m2) with painful mild and moderate knee osteoarthritis according to the Kellgren-Lawrence grading were recruited. Static standing balance was assessed while standing for 60 seconds on a force plate in three different footwear and two vision conditions: barefoot, wearing shoes without lateral wedged insoles and wearing shoes with lateral wedged insole in open and closed eye conditions. Pain intensity and static standing balance in the mediolateral direction (through the displacement and velocity of center of pressure) were investigated immediately and 4 weeks later.

Results: Lateral wedged insoles had no immediate effect on the center of pressure mediolateral displacement (P= 0.70) and velocity (P= 0.08). Using the lateral wedged insoles for 4 weeks resulted in significant improvement of pain (P< 0.001) in mediolateral center of pressure displacement (P< 0.001) and velocity (P< 0.001).

Conclusion: No significant immediate effect was seen on the average displacement and velocity of the center of pressure in the mediolateral direction while wearing lateral wedged insoles. Measured parameters improved after 4 weeks. Effect of lateral wedged insoles as a non-invasive treatment can be considered for improving the postural balance in those with knee osteoarthritis.