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As COVID-19 shows a heterogeneous spreading process globally, investigating factors associated with COVID-19 spreading among different countries will provide information for containment strategy and medical service decisions. A significant challenge for analyzing how these factors impact COVID-19 transmission is assessing key epidemiological parameters and how they change under different containment strategies across different nations. This paper builds a COVID-19 spread simulation model to estimate the core COVID-19 epidemiological parameters. Then, the correlation between these core COVID-19 epidemiological parameters and the times of publicly announced interventions is analyzed, including three typical countries, China (strictly containment), the USA (moderately control), and Sweden (loose control). Results show that the recovery rate leads to a distinct COVID-19 transmission process in the …