作者
Mario Liotti, Steven R Pliszka, Ricardo Perez, Delia Kothmann, Marty G Woldorff
发表日期
2005/1/1
期刊
Cortex
卷号
41
期号
3
页码范围
377-388
出版商
Elsevier
简介
Brain electrical activity associated with inhibitory control was recorded in ten ADHD and ten healthy children using high density event related potentials (ERPs) during the Stop Signal Task (SST). SST is a two-choice reaction time (RT) paradigm, in which subjects are required, on 25% of the trials, to withdraw their response upon presentation of a “Stop Signal”. In the healthy children, the ERP evoked by the Stop Signal differed for successful inhibitions (SI) compared to failed inhibitions (FI), with greater amplitude of a positive wave peaking around 320 msec over anterior medial frontal scalp (P3a). Such success-related P3a activity was significantly reduced in amplitude in the ADHD group. In addition, the error related negativity (ERN), a sharp negative wave that is present selectively on error trials in choice RT experiments, peaking 100 ms after motor onset, and distributed over anterior medial frontal scalp, was also …
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