作者
Mariana Schmajuk, Mario Liotti, Laura Busse, Marty G Woldorff
发表日期
2006/1/1
期刊
Neuropsychologia
卷号
44
期号
3
页码范围
384-395
出版商
Pergamon
简介
In a recent ERP study of inhibitory control using the Stop-Signal Task [Pliszka, S., Liotti, M., Woldorff, M. (2000). Inhibitory control in children with attention-deficit/hyperactivity disorder: Event-related potentials identify the processing component and timing of an impaired right-frontal response-inhibition mechanism. Biological Psychiatry, 48, 238–246], we showed that in normal children (age 10–12 years) the Stop Signals elicited a robust, right-frontal-maximal N200 (latency ∼200ms) that was strongly reduced in children with ADHD. To further investigate the mechanisms of response inhibition, this paradigm was applied to 11 healthy young adults. To better distinguish response-inhibition-related activity from early attentional effects, a “Stop-Signal-Irrelevant” condition was added, in which subjects performed the task while ignoring the Stop Signals. In the Stop-Signal-Relevant condition, the right frontal N200 to the …
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