作者
Francesco Squadrito, Herbert Marini, Alessandra Bitto, Domenica Altavilla, Francesca Polito, Elena Bianca Adamo, Rosario D'Anna, Vincenzo Arcoraci, Bruce P Burnett, Letteria Minutoli, Antonino Di Benedetto, Giacoma Di Vieste, Domenico Cucinotta, Cesare de Gregorio, Silvia Russo, Francesco Corrado, Antonino Saitta, Concetta Irace, Salvatore Corrao, Giuseppe Licata
发表日期
2013/8/1
期刊
The Journal of Clinical Endocrinology & Metabolism
卷号
98
期号
8
页码范围
3366-3374
出版商
Oxford University Press
简介
Context
This study was performed to evaluate the effects of genistein on metabolic and cardiovascular risk factors in Caucasian postmenopausal subjects with metabolic syndrome (MetS).
Objective
Our objective was to assess the effects of genistein on surrogate endpoints associated with diabetes and cardiovascular disease.
Design and Setting
This was a randomized, double-blind, placebo-controlled trial at 3 university medical centers in Italy.
Patients
Patients included 120 postmenopausal women with MetS according to modified Third Report of the National Cholesterol Education Program (NCEP), Expert Panel on Detection, Evaluation and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) criteria.
Intervention
After a 4-week stabilization period, postmenopausal women with MetS were …
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F Squadrito, H Marini, A Bitto, D Altavilla, F Polito… - The Journal of Clinical Endocrinology & Metabolism, 2013