作者
Luca Pasina, Codjo D Djade, Ugo Lucca, Alessandro Nobili, Mauro Tettamanti, Carlotta Franchi, Francesco Salerno, Salvatore Corrao, Alessandra Marengoni, Alfonso Iorio, Maura Marcucci, Francesco Violi, Pier Mannuccio Mannucci
发表日期
2013/2
期刊
Drugs & aging
卷号
30
页码范围
103-112
出版商
Springer International Publishing AG
简介
Background
Drugs with anticholinergic effects are associated with adverse events such as delirium and falls as well as cognitive decline and loss of independence.
Objective
The aim of the study was to evaluate the association between anticholinergic burden and both cognitive and functional status, according to the hypothesis that the cumulative anticholinergic burden, as measured by the Anticholinergic Cognitive Burden (ACB) Scale and Anticholinergic Risk Scale (ARS), increases the risk of cognitive decline and impairs activities of daily living.
Methods
This cross-sectional, prospective study (3-month telephone follow-up) was conducted in 66 Italian internal medicine and geriatric wards participating in the Registry of Polytherapies SIMI (Società Italiana di Medicina Interna) (REPOSI) study during 2010. The sample …
学术搜索中的文章
L Pasina, CD Djade, U Lucca, A Nobili, M Tettamanti… - Drugs & aging, 2013