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With new services emerging in fifth generation (5G)-advanced, the evolution in duplex modes plays an important role to meet more stringent requirements for both downlink (DL) and uplink (UL) transmissions. In this paper, sub-band full duplex (SBFD) at base station (BS) is studied as an attainable evolution of the traditional time division duplex (TDD). Both user equipment (UE) transparent SBFD and UE perceptive SBFD are proposed and studied to serve different types of UEs. To tackle the interference introduced by SBFD, a model including both BS self-interference and cross-link interference (CLI) is presented as a first step, and new interference management schemes are proposed. Three approaches to mitigate BS self-interference, namely the passive suppression, analog interference cancellation and digital interference cancellation are analyzed. A new framework for CLI management is illustrated along with …