作者
KL Johnston, E Louise Thomas, Jimmy D Bell, GS Frost, M Denise Robertson
发表日期
2010/4
期刊
Diabetic Medicine
卷号
27
期号
4
页码范围
391-397
出版商
Blackwell Publishing Ltd
简介
Diabet. Med. 27, 391–397 (2010)
Abstract
Aims Diets rich in non‐viscous fibre are linked to a reduced risk of both diabetes and cardiovascular disease; however, the mechanism of action remains unclear. This study was undertaken to assess whether chronic consumption of this type of fibre in individuals with the metabolic syndrome would improve insulin sensitivity via changes in ectopic fat storage.
Methods The study was a single‐blind, randomized, parallel nutritional intervention where 20 insulin resistant subjects consumed either the fibre supplement (resistant starch) (40 g/day) or placebo supplement (0 g/day) for 12 weeks. Insulin sensitivity was measured by euglycaemic–hyperinsulinaemic clamp and ectopic fat storage measured by whole‐body magnetic resonance spectroscopy.
Results Resistant starch consumption did not significantly affect body weight, fat storage in muscle, liver or visceral …
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KL Johnston, EL Thomas, JD Bell, GS Frost… - Diabetic Medicine, 2010