作者
Paul Elliott, David Haw, Haowei Wang, Oliver Eales, Caroline E Walters, Kylie EC Ainslie, Christina Atchison, Claudio Fronterre, Peter J Diggle, Andrew J Page, Alexander J Trotter, Sophie J Prosolek, COVID-19 Genomics UK (COG-UK) Consortium 11‡, Deborah Ashby, Christl A Donnelly, Wendy Barclay, Graham Taylor, Graham Cooke, Helen Ward, Ara Darzi, Steven Riley
发表日期
2021/11/2
期刊
Science
卷号
374
期号
6574
页码范围
eabl9551
出版商
American Association for the Advancement of Science
简介
BACKGROUND
The prevalence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection continues to drive rates of illness and hospitalizations despite high levels of vaccination, with the proportion of cases caused by the Delta lineage increasing in many populations. As vaccination programs roll out globally and social distancing is relaxed, future SARS-CoV-2 trends are uncertain.
METHODS
The Real-time Assessment of Community Transmission–1 (REACT-1) study has been tracking the spread of the COVID-19 pandemic in England since May 2020. The study involves obtaining a self-administered throat and nose swab for reverse transcription polymerase chain reaction (RT-PCR) from ~100,000 or more people during 2 to 3 weeks each month, based on random samples of the population in England at ages 5 years and above. As well as information on swab positivity, we collect …
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