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High-entropy alloys (HEAs), containing at least five major metal elements in equal or near equal atomic ratios, have drawn increasing attention because they open entirely new materials avenues for designing alloys with exceptional properties. In the literature, a well-studied equiatomic, face-centered cubic CrMnFeCoNi HEA reportedly exhibits a yield strength of 410 MPa and a ductility of 57% as well as a deformation mechanism of dislocation slip at room temperature [B. Gludovatz, et al., Science, 345 (2014) 1153–1158]. Some recent works also observed that twinning actually happens more or less in the equiatomic CrMnFeCoNi alloy at room temperature [Z.J. Zhang, et al., Nature Comm. 6 (2015) 10143]. In this study, we prepared a non-equiatomic, face-centered cubic Cr₂₆Mn₂₀Fe₂₀Co₂₀Ni₁₄ HEA with a comparatively low stacking fault energy (SFE) by making an appropriate adjustment of the composition …