作者
Weng Kit Lye, Euan Paterson, Christopher C Patterson, Alexander P Maxwell, Riswana Banu Binte Mohammed Abdul, E Shyong Tai, Ching Yu Cheng, Takamasa Kayama, Hidetoshi Yamashita, Mark Sarnak, Michael Shlipak, Kunihiro Matsushita, Unal Mutlu, Mohammad A Ikram, Caroline Klaver, Annette Kifley, Paul Mitchell, Chelsea Myers, Barbara E Klein, Ronald Klein, Tien Y Wong, Charumathi Sabanayagam, Gareth J McKay
发表日期
2021/3/1
来源
Kidney international
卷号
99
期号
3
页码范围
696-706
出版商
Elsevier
简介
Previously, variation in retinal vascular caliber has been reported in association with chronic kidney disease (CKD) but findings remain inconsistent. To help clarify this we conducted individual participant data meta-analysis and aggregate data meta-analysis on summary estimates to evaluate cross-sectional associations between retinal vascular caliber and CKD. A systematic review was performed using Medline and EMBASE for articles published until October 2018. The aggregate analysis used a two-stage approach combining summary estimates from eleven studies (44,803 patients) while the individual participant analysis used a one-stage approach combining raw data from nine studies (33,222 patients). CKD stages 3-5 was defined as an estimated glomerular filtration rate under 60 mL/min/1.73m2. Retinal arteriolar and venular caliber (central retinal arteriolar and venular equivalent) were assessed from …
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WK Lye, E Paterson, CC Patterson, AP Maxwell… - Kidney international, 2021