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Objectives:

Opioid-induced hyperalgesia (OIH) is a phenomenon whereby opioids increase patients’ pain sensitivity, complicating their use in analgesia. We explored practitioners’ attitudes towards, and knowledge concerning diagnosis, risk factors, and treatment of OIH.

Materials and Methods:

We administered an 18-item cross-sectional survey to 850 clinicians that managed chronic pain with opioid therapy.

Results:

The survey response rate was 37%(318/850). Most respondents (240/318, 76%) reported they had observed patients with OIH in their practice, of which 38%(84/222) reported OIH affected> 5% of their chronic pain patients. The majority (133/222, 60%) indicated that OIH could result from any dose of opioid therapy. The most commonly endorsed chronic pain conditions associated with the development of OIH were fibromyalgia (109/216, 51%) and low back pain (91/216, 42%), while 42%(91/216 …