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Hybrid material combines organic-inorganic substituents that can impose hydrophilicity and anti-biofouling properties in polymeric membranes. In this study, ginger extract-silica nanoparticles (GE-SiNPs) hybrid materials were synthesized through the sol-gel technique and was applied as a new additive to improve polyvinylidene fluoride (PVDF) membrane properties. Ginger (Zingiber officinale Roscoe) extract (GE) contains phenol derivatives that provide anti-microbial properties; while silica nanoparticles (SiNPs) plays role to increase membrane hydrophilicity and prevent organic fouling. The PVDF/GE-SiNPs membrane was prepared using non-solvent induced phase separation method and was applied to concentrate Bovine Serum Albumin (BSA). The resulted membranes were characterized in terms of morphology, hydrophilicity, tensile strength, porosity, pure water flux, antibacterial property, and its …