作者
Scott M Stevens, Scott C Woller, Lisa Baumann Kreuziger, Henri Bounameaux, Kevin Doerschug, Geert-Jan Geersing, Menno V Huisman, Clive Kearon, Christopher S King, Andrew J Knighton, Erica Lake, Susan Murin, Janine RE Vintch, Philip S Wells, Lisa K Moores
发表日期
2021/12/1
期刊
Chest
卷号
160
期号
6
页码范围
2247-2259
出版商
Elsevier
简介
Background
This is the 2nd update to the 9th edition of these guidelines. We provide recommendations on 17 PICO (Population, Intervention, Comparator, Outcome) questions, four of which have not been addressed previously.
Methods
We generate strong and weak recommendations based on high-, moderate-, and low-certainty evidence, using GRADE (Grading of Recommendations, Assessment, Development, and Evaluation) methodology.
Results
The panel generated 29 guidance statements, 13 of which are graded as strong recommendations, covering aspects of antithrombotic management of VTE from initial management through secondary prevention and risk reduction of postthrombotic syndrome. Four new guidance statements have been added that did not appear in the 9th edition (2012) or 1st update (2016). Eight statements have been substantially modified from the 1st update.
Conclusion
New evidence …
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SM Stevens, SC Woller, LB Kreuziger, H Bounameaux… - Chest, 2021