作者
Alessandro G Fois, Panagiotis Paliogiannis, Salvatore Sotgia, Arduino A Mangoni, Elisabetta Zinellu, Pietro Pirina, Ciriaco Carru, Angelo Zinellu
发表日期
2018/12
来源
Respiratory Research
卷号
19
页码范围
1-13
出版商
BioMed Central
简介
Introduction
Idiopathic pulmonary fibrosis (IPF), a fatal lung disease of unknown origin, is characterized by chronic and progressive fibrosing interstitial pneumonia which progressively impairs lung function. Oxidative stress is one of the main pathogenic pathways in IPF. The aim of this systematic review was to describe the type of markers of oxidative stress identified in different biological specimens and the effects of antioxidant therapies in patients with IPF.
Methods
We conducted a systematic search of publications listed in electronic databases (Pubmed, Web of Science, Scopus and Google Scholar) from inception to October 2017. Two investigators independently reviewed all identified articles to determine eligibility.
Results
After a substantial proportion of the initially identified articles (n = 554) was excluded …
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AG Fois, P Paliogiannis, S Sotgia, AA Mangoni… - Respiratory Research, 2018