作者
Zahid Yaqoob, Toyohiko Yamauchi, Wonshik Choi, Dan Fu, Ramachandra R Dasari, Michael S Feld
发表日期
2011/4/11
期刊
Optics express
卷号
19
期号
8
页码范围
7587-7595
出版商
Optica Publishing Group
简介
We present a full-field reflection phase microscope that combines low-coherence interferometry and off-axis digital holographic microscopy (DHM). The reflection-based DHM provides highly sensitive and a single-shot imaging of cellular dynamics while the use of low coherence source provides a depth-selective measurement. The setup uniquely uses a diffraction grating in the reference arm to generate an interference image of uniform contrast over the entire field-of-view albeit low-coherence light source. We have measured the path-length sensitivity of our instrument to be approximately 21?picometers/Hz that makes it suitable for nanometer-scale full-field measurement of membrane dynamics in live cells.
引用总数
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学术搜索中的文章
Z Yaqoob, T Yamauchi, W Choi, D Fu, RR Dasari… - Optics express, 2011
Z Yaqoob, W Choi, T Yamauchi, M Feld - US Patent 10,451,402, 2019