作者
Richard Border, Robin P Corley, Sandra A Brown, John K Hewitt, Christian J Hopfer, Shannon K McWilliams, Sally Ann Rhea, Christen L Shriver, Michael C Stallings, Tamara L Wall, Kerri E Woodward, Soo Hyun Rhee
发表日期
2018/11
期刊
Addiction
卷号
113
期号
11
页码范围
2107-2115
简介
Background and aims
Adolescents with conduct and substance use problems are at increased risk for premature mortality, but the extent to which these risk factors reflect family‐ or individual‐level differences and account for shared or unique variance is unknown. This study examined common and independent contributions to mortality hazard in adolescents ascertained for conduct disorder (CD) and substance use disorder (SUD), their siblings and community controls, hypothesizing that individual differences in CD and SUD severity would explain unique variation in mortality risk beyond that due to clinical/control status and demographic factors.
Design
Mortality analysis in a prospective study (Genetics of Antisocial Drug Dependence Study) that began in 1993.
Setting
Multi‐site sample recruited in San Diego, California and Denver, Colorado, USA.
Participants
A total of 1463 clinical probands were recruited …
引用总数
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