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A computerized optimization method, system, and computer readable storage medium for performing pattern searching includes (a) providing an initial mesh of vectors;(b) pro viding initial points to be used as a base vector establishing a center region of the mesh of vectors;(c) for each base vector, obtaining a transformed mesh via an isometric trans formation of the initial mesh of vectors;(d) evaluating the model objective function via each transformed mesh of vectors;(e) selecting a next set of base vectors by selecting a most favorable set of transformed mesh vectors to corre spond with the objective function;(f) repeating steps (c) through (e) in an iterative sequence until a termination criterion of the iterative sequence is met; and (g) storing the selected most favorable transformed mesh vectors in a memory.