作者
Sandro Rossi, Francesca Torello Viera, Giorgia Ghittoni, Lorenzo Cobianchi, Laura Lavinia Rosa, Luisa Siciliani, Chandra Bortolotto, Letizia Veronese, Alessandro Vercelli, Anna Gallotti, Valentina Ravetta
发表日期
2014/8/1
期刊
Pancreas
卷号
43
期号
6
页码范围
938-945
出版商
LWW
简介
Objective
This study aimed to assess the feasibility, safety, and efficacy of radiofrequency ablation (RFA) of pancreatic neuroendocrine tumors (PNETs).
Methods
We performed RFA on 10 patients (7 women) aged 38 to 75 years with histologically diagnosed PNETs (secreting in 3 cases) who could not or would not undergo surgical resection. Tumor nodules (diameter, 0.9-2.9 cm; mean [SD], 1.6 [0.5] cm) were located in the head (n= 7) or body (n= 3) of the pancreas. Ultrasound-guided RFA was performed percutaneously (n= 7), endoscopically (n= 1), or intraoperatively (n= 2) using commercially available equipment. Complete ablation was defined as absence of enhancing tissue at the tumor site on contrast-enhanced imaging studies and normalization of previously elevated serum hormone levels.
Results
Complete ablation was achieved with 1 (n= 9) or 2 (n= 1) RFA procedures. All neuroendocrine syndromes …
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S Rossi, FT Viera, G Ghittoni, L Cobianchi, LL Rosa… - Pancreas, 2014