作者
Michael J Peluso, Tyler-Marie Deveau, Sadie E Munter, Dylan Ryder, Amanda Buck, Gabriele Beck-Engeser, Fay Chan, Scott Lu, Sarah A Goldberg, Rebecca Hoh, Viva Tai, Leonel Torres, Nikita S Iyer, Monika Deswal, Lynn H Ngo, Melissa Buitrago, Antonio Rodriguez, Jessica Y Chen, Brandon C Yee, Ahmed Chenna, John W Winslow, Christos J Petropoulos, Amelia N Deitchman, Joanna Hellmuth, Matthew A Spinelli, Matthew S Durstenfeld, Priscilla Y Hsue, J Daniel Kelly, Jeffrey N Martin, Steven G Deeks, Peter W Hunt, Timothy J Henrich
发表日期
2023/2/1
期刊
The Journal of clinical investigation
卷号
133
期号
3
出版商
American Society for Clinical Investigation
简介
BACKGROUND
The presence and reactivation of chronic viral infections, such as EBV, CMV, and HIV, have been proposed as potential contributors to long COVID (LC), but studies in well-characterized postacute cohorts of individuals with COVID-19 over a longer time course consistent with current case definitions of LC are limited.
METHODS
In a cohort of 280 adults with prior SARS-CoV-2 infection, we assessed the presence and types of LC symptoms and prior medical history (including COVID-19 history and HIV status) and performed serological testing for EBV and CMV using a commercial laboratory. We used covariate-adjusted binary logistic regression models to identify independent associations between variables and LC symptoms.
RESULTS
We observed that LC symptoms, such as fatigue and neurocognitive dysfunction, at a median of 4 months …
学术搜索中的文章
MJ Peluso, TM Deveau, SE Munter, D Ryder, A Buck… - The Journal of clinical investigation, 2023