作者
Philippe Généreux, Mahesh V Madhavan, Gary S Mintz, Akiko Maehara, Tullio Palmerini, Laura LaSalle, Ke Xu, Tom McAndrew, Ajay Kirtane, Alexandra J Lansky, Sorin J Brener, Roxana Mehran, Gregg W Stone
发表日期
2014/5/13
期刊
Journal of the American College of Cardiology
卷号
63
期号
18
页码范围
1845-1854
出版商
American College of Cardiology Foundation
简介
Objectives
This study sought to determine the frequency and impact of coronary calcification among patients undergoing percutaneous coronary intervention (PCI) for acute coronary syndromes (ACS).
Background
Small studies in patients with stable coronary artery disease have suggested a worse prognosis after PCI of calcified compared with noncalcified lesions. Little is known about the impact of coronary calcification on outcomes after PCI for patients presenting with non–ST-segment elevation and ST-segment elevation ACS.
Methods
Data from 6,855 patients presenting with ACS in whom PCI was performed were pooled from 2 large-scale randomized, controlled trials, ACUITY (Acute Catheterization and Urgent Intervention Triage Strategy) and HORIZONS-AMI (Harmonizing Outcomes With Revascularization and Stents in Acute Myocardial Infarction). One-year outcomes were analyzed according to the severity …
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P Généreux, MV Madhavan, GS Mintz, A Maehara… - Journal of the American College of Cardiology, 2014