作者
Sudhir Tauro, Charles Craddock, Karl Peggs, Gulnaz Begum, Premini Mahendra, Gordon Cook, Judith Marsh, Donald Milligan, Anthony Goldstone, Ann Hunter, Asim Khwaja, Raj Chopra, Timothy Littlewood, Andrew Peniket, Anne Parker, Graham Jackson, Geoff Hale, Mark Cook, Nigel Russell, Stephen Mackinnon
发表日期
2005/12/20
期刊
Journal of Clinical Oncology
卷号
23
期号
36
页码范围
9387-9393
出版商
American Society of Clinical Oncology
简介
Purpose
The toxicity of allogeneic stem-cell transplantation can be substantially reduced using a reduced-intensity conditioning (RIC) regimen. This has increased the proportion of patients with myeloid malignancies eligible for allogeneic transplantation. However, the capacity of RIC allografts to produce durable remissions in patients with acute myeloid leukemia (AML) and myelodysplasia (MDS) has not yet been defined, and consequently, the role of RIC allografts in the management of these diseases remains conjectural.
引用总数
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