作者
Kristin M D’Silva, Naomi Serling-Boyd, Rachel Wallwork, Tiffany Hsu, Xiaoqing Fu, Ellen M Gravallese, Hyon K Choi, Jeffrey A Sparks, Zachary S Wallace
发表日期
2020/9/1
期刊
Annals of the rheumatic diseases
卷号
79
期号
9
页码范围
1156-1162
出版商
BMJ Publishing Group Ltd
简介
Objective
To investigate differences in manifestations and outcomes of coronavirus disease 2019 (COVID-19) infection between those with and without rheumatic disease.
Methods
We conducted a comparative cohort study of patients with rheumatic disease and COVID-19 (confirmed by severe acute respiratory syndrome coronavirus 2 PCR), compared in a 1:2 ratio with matched comparators on age, sex and date of COVID-19 diagnosis, between 1 March and 8 April 2020, at Partners HealthCare System in the greater Boston, Massachusetts area. We examined differences in demographics, clinical features and outcomes of COVID-19 infection. The main outcomes were hospitalisation, intensive care admission, mechanical ventilation and mortality.
Results
We identified 52 rheumatic disease patients with COVID-19 (mean age, 63 years; 69% female) and matched these to 104 non-rheumatic disease comparators. The …
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KM D'Silva, N Serling-Boyd, R Wallwork, T Hsu, X Fu… - Annals of the rheumatic diseases, 2020