作者
Yumeko Kawano, Naomi J Patel, Xiaosong Wang, Claire E Cook, Kathleen MM Vanni, Emily N Kowalski, Emily P Banasiak, Grace Qian, Michael DiIorio, Tiffany YT Hsu, Michael E Weinblatt, Derrick J Todd, Zachary S Wallace, Jeffrey A Sparks
发表日期
2022/12/1
期刊
Annals of the rheumatic diseases
卷号
81
期号
12
页码范围
1742-1749
出版商
BMJ Publishing Group Ltd
简介
Objectives
To investigate temporal trends in incidence and severity of COVID-19 among patients with systemic autoimmune rheumatic diseases (SARDs) from the first wave through the initial Omicron wave.
Methods
We conducted a retrospective cohort study investigating COVID-19 outcomes among patientswith SARD systematically identified to have confirmed COVID-19 from 1 March 2020 to 31 January 2022 at Mass General Brigham. We tabulated COVID-19 counts of total and severe cases (hospitalisations or deaths) and compared the proportion with severe COVID-19 by calendar period and by vaccination status. We used logistic regression to estimate the ORs for severe COVID-19 for each period compared with the early COVID-19 period (reference group).
Results
We identified 1449 patients with SARD with COVID-19 (mean age 58.4 years, 75.2% female, 33.9% rheumatoid arthritis). There were 399 (28 …
引用总数