作者
Virginie Nerich, Prevost Jantchou, M‐C Boutron‐Ruault, Elisabeth Monnet, Alain Weill, Vincent Vanbockstael, G‐R Auleley, Corinne Balaire, Patrick Dubost, Stéphane Rican, Hubert Allemand, Franck Carbonnel
发表日期
2011/4
期刊
Alimentary pharmacology & therapeutics
卷号
33
期号
8
页码范围
940-945
出版商
Blackwell Publishing Ltd
简介
Aliment Pharmacol Ther 2011; 33: 940–945
Summary
Background Low sunshine exposure might contribute to the pathogenesis of inflammatory bowel disease (IBD).
Aim To assess the geographic distribution of IBD incidence in relation to sunshine exposure in France to test the hypothesis that higher sun exposure is associated with lower IBD risk.
Methods Using the national health insurance database, incidence rates of Crohn’s disease (CD) and ulcerative colitis (UC) were estimated for each of the 94 French administrative areas (‘départements’), between 2000 and 2002. The surface UV radiation intensity was obtained by combining modelling and satellite data from Meteosat, the European meteorological satellite. Relationships between incidence rates and sun exposure were tested for significance by using a Poisson regression. We mapped smoothed relative risks (sRR) for CD and UC, using a …
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V Nerich, P Jantchou, MC Boutron‐Ruault, E Monnet… - Alimentary pharmacology & therapeutics, 2011