作者
Gregg C Fonarow, Wendy Gattis Stough, William T Abraham, Nancy M Albert, Mihai Gheorghiade, Barry H Greenberg, Christopher M O’Connor, Jie Lena Sun, Clyde W Yancy, James B Young, OPTIMIZE-HF Investigators and hospitals
发表日期
2007/8/21
期刊
Journal of the American College of Cardiology
卷号
50
期号
8
页码范围
768-777
出版商
American College of Cardiology Foundation
简介
Objectives
We sought to evaluate the characteristics, treatments, and outcomes of patients with preserved and reduced systolic function heart failure (HF).
Background
Heart failure with preserved systolic function (PSF) is common but not well understood.
Methods
This analysis of the OPTIMIZE-HF (Organized Program to Initiate Lifesaving Treatment in Hospitalized Patients With Heart Failure) registry compared 20,118 patients with left ventricular systolic dysfunction (LVSD) and 21,149 patients with PSF (left ventricular ejection fraction [EF] ≥40%). Sixty- to 90-day follow-up was obtained in a pre-specified 10% sample of patients. Analyses of patients with PSF defined as EF >50% were also performed for comparison.
Results
Patients with PSF (EF ≥40%) were more likely to be older, female, and Caucasian and to have a nonischemic etiology. Although length of hospital stay was the same in both groups, risk of in …
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GC Fonarow, WG Stough, WT Abraham, NM Albert… - Journal of the American College of Cardiology, 2007