作者
A Zida, S Bamba, A Yacouba, R Ouedraogo-Traore, RT Guiguemdé
发表日期
2017/3/1
来源
Journal de mycologie medicale
卷号
27
期号
1
页码范围
1-19
出版商
Elsevier Masson
简介
Introduction
Candida albicans is the most prevalent fungal pathogen in humans. Due to the development of drug resistance, there is today a need for new antifungal agents for the efficient management of C. albicans infections. Therefore, we reviewed antifungal activity, mechanisms of action, possible synergism with antifungal drugs of all natural substances experimented to be efficient against C. albicans for future.
Methods
An extensive and systematic review of the literature was undertaken and all relevant abstracts and full-text articles analyzed and included in the review.
Review
A total of 111 documents were published and highlighted 142 anti-C. albicans natural products. These products are mostly are reported in Asia (44.37%) and America (28.17%). According to in vitro model criteria, from the 142 natural substances, antifungal activity can be considered as important for 40 (28.20%) and moderate for 24 (16.90 …
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