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Hyperbolic metamaterials (HMMs) have emerged as a burgeoning field of research over the past few years as their dispersion can be easily engineered in different spectral regions using various material combinations. Even though HMMs have comparatively low optical loss due to a single resonance, the noble‐metal‐based HMMs are limited by their strong energy dissipation in metallic layers at visible frequencies. Here, the fabrication of noble‐metal‐free reconfigurable HMMs for visible photonic applications is experimentally demonstrated. The low‐loss and active HMMs are realized by combining titanium nitride (TiN) and stibnite (Sb₂S₃) as the phase change material. A reconfigurable plasmonic biosensor platform based on active Sb₂S₃–TiN HMMs is proposed, and it is shown that significant improvement in sensitivity is possible for small molecule detection at low concentrations. In addition, a plasmonic apta …