Integrative approaches for large-scale transcriptome-wide association studies A Gusev, A Ko, H Shi, G Bhatia, W Chung, BWJH Penninx, R Jansen, ... Nature genetics 48 (3), 245-252, 2016 | 1817 | 2016 |
Mapping the human genetic architecture of COVID-19 Writing group Writing group leaders Pathak Gita A. 6 Andrews Shea J. 7 Kanai ... Nature 600 (7889), 472-477, 2021 | 741 | 2021 |
Contrasting the genetic architecture of 30 complex traits from summary association data H Shi, G Kichaev, B Pasaniuc American Journal of Human Genetics 99 (1), 139–153, 2016 | 402 | 2016 |
Probabilistic fine-mapping of transcriptome-wide association studies N Mancuso, MK Freund, R Johnson, H Shi, G Kichaev, A Gusev, ... Nature genetics 51 (4), 675-682, 2019 | 300 | 2019 |
Shared genetic and experimental links between obesity-related traits and asthma subtypes in UK Biobank Z Zhu, Y Guo, H Shi, CL Liu, RA Panganiban, W Chung, LJ O'Connor, ... Journal of Allergy and Clinical Immunology 145 (2), 537-549, 2020 | 279 | 2020 |
Integrating gene expression with summary association statistics to identify genes associated with 30 complex traits N Mancuso, H Shi, P Goddard, G Kichaev, A Gusev, B Pasaniuc The American Journal of Human Genetics 100 (3), 473-487, 2017 | 261 | 2017 |
Local genetic correlation gives insights into the shared genetic architecture of complex traits H Shi, N Mancuso, S Spendlove, B Pasaniuc The American Journal of Human Genetics 101 (5), 737-751, 2017 | 256 | 2017 |
A Bayesian framework for multiple trait colocalization from summary association statistics C Giambartolomei, J Zhenli Liu, W Zhang, M Hauberg, H Shi, J Boocock, ... Bioinformatics 34 (15), 2538-2545, 2018 | 237 | 2018 |
Fast and accurate imputation of summary statistics enhances evidence of functional enrichment B Pasaniuc, N Zaitlen, H Shi, G Bhatia, A Gusev, J Pickrell, J Hirschhorn, ... Bioinformatics 30 (20), 2906-2914, 2014 | 220 | 2014 |
Leveraging fine-mapping and multipopulation training data to improve cross-population polygenic risk scores O Weissbrod*, M Kanai*, H Shi*, S Gazal, WJ Peyrot, AV Khera, Y Okada, ... Nature Genetics, 1-9, 2022 | 164* | 2022 |
Population-specific causal disease effect sizes in functionally important regions impacted by selection H Shi, S Gazal, M Kanai, EM Koch, AP Schoech, KM Siewert, SS Kim, ... Nature communications 12 (1), 1098, 2021 | 138 | 2021 |
Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis Z Zhu, X Zhu, CL Liu, H Shi, S Shen, Y Yang, K Hasegawa, CA Camargo, ... European Respiratory Journal 54 (6), 2019 | 129 | 2019 |
Technology dictates algorithms: recent developments in read alignment M Alser, J Rotman, D Deshpande, K Taraszka, H Shi, PI Baykal, HT Yang, ... Genome biology 22 (1), 249, 2021 | 112 | 2021 |
Epigenome-wide association of liver methylation patterns and complex metabolic traits in mice LD Orozco, M Morselli, L Rubbi, W Guo, J Go, H Shi, D Lopez, NA Furlotte, ... Cell metabolism 21 (6), 905-917, 2015 | 109 | 2015 |
Accurate estimation of SNP-heritability from biobank-scale data irrespective of genetic architecture K Hou, KS Burch, A Majumdar, H Shi, N Mancuso, Y Wu, S Sankararaman, ... Nature Genetics 51, 1244–1251, 2019 | 105 | 2019 |
Combining SNP-to-gene linking strategies to identify disease genes and assess disease omnigenicity S Gazal, O Weissbrod, F Hormozdiari, KK Dey, J Nasser, KA Jagadeesh, ... Nature Genetics 54 (6), 827-836, 2022 | 90 | 2022 |
Phenotype-specific enrichment of Mendelian disorder genes near GWAS regions across 62 complex traits MK Freund, KS Burch, H Shi, N Mancuso, G Kichaev, KM Garske, DZ Pan, ... The American Journal of Human Genetics 103 (4), 535-552, 2018 | 89 | 2018 |
Localizing components of shared transethnic genetic architecture of complex traits from GWAS summary data H Shi*, KS Burch*, R Johnson, MK Freund, G Kichaev, N Mancuso, ... The American Journal of Human Genetics 106 (6), 805-817, 2020 | 78 | 2020 |
The missing link between genetic association and regulatory function NJ Connally, S Nazeen, D Lee, H Shi, J Stamatoyannopoulos, S Chun, ... Elife 11, e74970, 2022 | 74 | 2022 |
Atlas of prostate cancer heritability in European and African-American men pinpoints tissue-specific regulation A Gusev, H Shi, G Kichaev, M Pomerantz, F Li, HW Long, SA Ingles, ... Nature communications 7 (1), 10979, 2016 | 54 | 2016 |