Improving polygenic prediction in ancestrally diverse populations Y Ruan, YF Lin, YCA Feng, CY Chen, M Lam, Z Guo, L He, A Sawa, ... Nature genetics 54 (5), 573-580, 2022 | 177 | 2022 |
Comparative genome analysis of Prevotella intermedia strain isolated from infected root canal reveals features related to pathogenicity and adaptation Y Ruan, L Shen, Y Zou, Z Qi, J Yin, J Jiang, L Guo, L He, Z Chen, Z Tang, ... BMC genomics 16 (1), 1-21, 2015 | 49 | 2015 |
Genetic Association of Curative and Adverse Reactions to Tyrosine Kinase Inhibitors in Chinese advanced Non-Small Cell Lung Cancer patients XZSQ Yunfeng Ruan, Jie Jiang, Liang Guo, Yan Li, Hailiang Huang, Lu Shen ... Scientific Reports 6 (doi:10.1038/srep23368), 2016 | 21 | 2016 |
An Engineered Rare Codon Device for Optimization of Metabolic Pathways LHGM You Wang, Chunying Li, Md. Rezaul Islam Khan, Yushu Wang, Yunfeng Ruan ... Scientific Reports 6, 2016 | 16 | 2016 |
The power of pathway-based polygenic risk scores SW Choi, J Garcia-Gonzalez, Y Ruan, HM Wu, J Johnson, C Hoggart, ... | 14* | 2021 |
Functional characterization of human CYP2C9 allelic variants in COS-7 cells H Du, Z Wei, Y Yan, Y Xiong, X Zhang, L Shen, Y Ruan, X Wu, Q Xu, L He, ... Frontiers in Pharmacology 7, 98, 2016 | 11 | 2016 |
Genetic association of drug response to erlotinib in Chinese advanced non-small cell lung cancer patients C Wang, F Chen, Y Liu, Q Xu, L Guo, X Zhang, Y Ruan, Y Shi, L Shen, ... Frontiers in pharmacology 9, 360, 2018 | 9 | 2018 |
PRSet: Pathway-based polygenic risk score analyses and software SW Choi, J García-González, Y Ruan, HM Wu, C Porras, J Johnson, ... PLoS genetics 19 (2), e1010624, 2023 | 8 | 2023 |
Measured blood pressure, genetically predicted blood pressure, and cardiovascular disease risk in the UK biobank SMJ Cho, S Koyama, Y Ruan, K Lannery, M Wong, E Ajufo, H Lee, ... JAMA cardiology 7 (11), 1129-1137, 2022 | 6 | 2022 |
p. E95K mutation in Indian hedgehog causing brachydactyly type A1 impairs IHH/Gli1 downstream transcriptional regulation L Shen, G Ma, Y Shi, Y Ruan, X Yang, X Wu, Y Xiong, C Wan, C Yang, ... BMC genetics 20, 1-9, 2019 | 5 | 2019 |
INVESTIGATING SHRINKAGE METHODS TO IMPROVE ACCURACY OF GWAS AND PRS EFFECT SIZE ESTIMATES Y Ruan, SW Choi, P O'Reilly European Neuropsychopharmacology 29, S896-S897, 2019 | 2 | 2019 |
Integrative polygenic risk score improves the prediction accuracy of complex traits and diseases B Truong, LE Hull, Y Ruan, QQ Huang, W Hornsby, H Martin, DA van Heel, ... medRxiv, 2023.02. 21.23286110, 2023 | 1 | 2023 |
Polygenic score informed by genome-wide association studies of multiple ancestries and related traits improves risk prediction for coronary artery disease AP Patel, M Wang, Y Ruan, S Koyama, SL Clarke, X Yang, C Tcheandjieu, ... medRxiv, 2023.03. 03.23286649, 2023 | 1 | 2023 |
Author Correction: Improving polygenic prediction in ancestrally diverse populations Y Ruan, YF Lin, YCA Feng, CY Chen, M Lam, Z Guo, L He, A Sawa, ... Nature Genetics 54 (8), 1259-1259, 2022 | 1 | 2022 |
A multi-ancestry polygenic risk score improves risk prediction for coronary artery disease AP Patel, M Wang, Y Ruan, S Koyama, SL Clarke, X Yang, C Tcheandjieu, ... Nature Medicine, 1-11, 2023 | | 2023 |
Birth Weight Is Associated With Clonal Hematopoiesis of Indeterminate Potential and Cardiovascular Outcomes in Adulthood A Schuermans, T Nakao, Y Ruan, S Koyama, Z Yu, MM Uddin, ... Journal of the American Heart Association, e030220, 2023 | | 2023 |
Genetic modification of inflammation and clonal hematopoiesis-associated cardiovascular risk Z Yu, TP Fidler, Y Ruan, C Vlasschaert, T Nakao, MM Uddin, T Mack, ... medRxiv, 2022.12. 08.22283237, 2022 | | 2022 |
Venous Thromboembolism Polygenic Risk Score Associates With Pulmonary Hypertension in the UK Biobank KR Clapham, M Mesbah Uddin, MC Honigberg, T Gilliland, Y Ruan, ... Circulation: Genomic and Precision Medicine 15 (6), e003797, 2022 | | 2022 |
Metabolomic Profiles Differentiate Arterial and Venous Polygenic Risk TC Gilliland, J Lee, Y Ruan, B Truong, S Haidermota, K Lannery, M Wong, ... Circulation 146 (Suppl_1), A11954-A11954, 2022 | | 2022 |
Measured Blood Pressure, Genetically Predicted Blood Pressure, And Cardiovascular Disease Risk SMJ Cho, S Koyama, Y Ruan, K Lannery, M Wong, E Ajufo, H Lee, ... Hypertension 79 (Suppl_1), A136-A136, 2022 | | 2022 |