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Eiji Hara
Eiji Hara
在 biken.osaka-u.ac.jp 的电子邮件经过验证
标题
引用次数
引用次数
年份
Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretome
S Yoshimoto, TM Loo, K Atarashi, H Kanda, S Sato, S Oyadomari, ...
Nature 499 (7456), 97-101, 2013
22222013
Cellular senescence: defining a path forward
V Gorgoulis, PD Adams, A Alimonti, DC Bennett, O Bischof, C Bishop, ...
Cell 179 (4), 813-827, 2019
19652019
An essential role for senescent cells in optimal wound healing through secretion of PDGF-AA
M Demaria, N Ohtani, SA Youssef, F Rodier, W Toussaint, JR Mitchell, ...
Developmental cell 31 (6), 722-733, 2014
18252014
The alternative product from the human CDKN2A locus, p14ARF, participates in a regulatory feedback loop with p53 and MDM2
FJ Stott, S Bates, MC James, BB McConnell, M Starborg, S Brookes, ...
The EMBO journal 17 (17), 5001-5014, 1998
15171998
Regulation of p16CDKN2 expression and its implications for cell immortalization and senescence
E Hara, R Smith, D Parry, H Tahara, S Stone, G Peters
Molecular and cellular biology, 1996
10001996
Opposing effects of Ets and Id proteins on p16INK4a expression during cellular senescence
N Ohtani, Z Zebedee, TJG Huot, JA Stinson, M Sugimoto, Y Ohashi, ...
Nature 409 (6823), 1067-1070, 2001
7992001
Exosomes maintain cellular homeostasis by excreting harmful DNA from cells
A Takahashi, R Okada, K Nagao, Y Kawamata, A Hanyu, S Yoshimoto, ...
Nature communications 8 (1), 15287, 2017
7032017
Mitogenic signalling and the p16INK4a–Rb pathway cooperate to enforce irreversible cellular senescence
A Takahashi, N Ohtani, K Yamakoshi, S Iida, H Tahara, K Nakayama, ...
Nature cell biology 8 (11), 1291-1297, 2006
5922006
Genotoxic stress abrogates renewal of melanocyte stem cells by triggering their differentiation
K Inomata, T Aoto, NT Binh, N Okamoto, S Tanimura, T Wakayama, ...
Cell 137 (6), 1088-1099, 2009
4222009
The p16INK4a-RB pathway: molecular link between cellular senescence and tumor suppression
N Ohtani, K Yamakoshi, A Takahashi, E Hara
The Journal of Medical Investigation 51 (3, 4), 146-153, 2004
4102004
Gut Microbiota Promotes Obesity-Associated Liver Cancer through PGE2-Mediated Suppression of Antitumor Immunity
TM Loo, F Kamachi, Y Watanabe, S Yoshimoto, H Kanda, Y Arai, ...
Cancer discovery 7 (5), 522-538, 2017
4042017
Id-related genes encoding helix-loop-helix proteins are required for G1 progression and are repressed in senescent human fibroblasts.
E Hara, T Yamaguchi, H Nojima, T Ide, J Campisi, H Okayama, K Oda
Journal of Biological Chemistry 269 (3), 2139-2145, 1994
3971994
Cooperative effect of antisense-Rb and antisense-p53 oligomers on the extension of life span in human diploid fibroblasts, TIG-1
E Hara, H Tsurui, A Shinozaki, S Nakada, K Oda
Biochemical and biophysical research communications 179 (1), 528-534, 1991
3471991
Small extracellular vesicles secreted from senescent cells promote cancer cell proliferation through EphA2
M Takasugi, R Okada, A Takahashi, D Virya Chen, S Watanabe, E Hara
Nature communications 8 (1), 15729, 2017
3382017
Id proteins in cell cycle control and cellular senescence
Z Zebedee, E Hara
Oncogene 20 (58), 8317-8325, 2001
3332001
Induced expression of p16INK4a inhibits both CDK4-and CDK2-associated kinase activity by reassortment of cyclin-CDK-inhibitor complexes
BB McConnell, FJ Gregory, FJ Stott, E Hara, G Peters
Molecular and cellular biology, 1999
3151999
Impact of senescence‐associated secretory phenotype and its potential as a therapeutic target for senescence‐associated diseases
S Watanabe, S Kawamoto, N Ohtani, E Hara
Cancer science 108 (4), 563-569, 2017
3122017
Subtractive cDNA cloning using oligo(dt) 30 -latex and PCR: isolation of cDNA clones specific to undifferentiated human embryonal carcinoma cells
E Hara, T Kato, S Nakada, S Sekiya, K Oda
Nucleic Acids Research 19 (25), 7097-7104, 1991
3031991
Downregulation of cytoplasmic DNases is implicated in cytoplasmic DNA accumulation and SASP in senescent cells
A Takahashi, TM Loo, R Okada, F Kamachi, Y Watanabe, M Wakita, ...
Nature communications 9 (1), 1249, 2018
2792018
Suppression of mammary epithelial cell differentiation by the helix-loop-helix protein Id-1
PY Desprez, E Hara, MJ Bissell, J Campisi
Molecular and cellular biology, 1995
2371995
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