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Marcus Järås
Marcus Järås
在 med.lu.se 的电子邮件经过验证
标题
引用次数
引用次数
年份
Lenalidomide induces ubiquitination and degradation of CK1α in del (5q) MDS
J Krönke, EC Fink, PW Hollenbach, KJ MacBeth, SN Hurst, ND Udeshi, ...
Nature 523 (7559), 183-188, 2015
8232015
Core circadian clock genes regulate leukemia stem cells in AML
RV Puram, MS Kowalczyk, CG de Boer, RK Schneider, PG Miller, ...
Cell 165 (2), 303-316, 2016
2342016
Isolation and killing of candidate chronic myeloid leukemia stem cells by antibody targeting of IL-1 receptor accessory protein
M Järås, P Johnels, N Hansen, H Ågerstam, P Tsapogas, M Rissler, ...
Proceedings of the National Academy of Sciences 107 (37), 16280-16285, 2010
2232010
Role of casein kinase 1A1 in the biology and targeted therapy of del (5q) MDS
RK Schneider, V Adema, D Heckl, M Järås, M Mallo, AM Lord, LP Chu, ...
Cancer cell 26 (4), 509-520, 2014
2062014
In Vivo RNAi screening identifies a leukemia-specific dependence on integrin beta 3 signaling
PG Miller, F Al-Shahrour, KA Hartwell, LP Chu, M Järås, RV Puram, ...
Cancer cell 24 (1), 45-58, 2013
1802013
Development of an adenoviral vector system with adenovirus serotype 35 tropism; efficient transient gene transfer into primary malignant hematopoietic cells
M Nilsson, J Ljungberg, J Richter, T Kiefer, M Magnusson, A Lieber, ...
The Journal of Gene Medicine: A cross‐disciplinary journal for research on …, 2004
1472004
Niche-based screening identifies small-molecule inhibitors of leukemia stem cells
KA Hartwell, PG Miller, S Mukherjee, AR Kahn, AL Stewart, DJ Logan, ...
Nature chemical biology 9 (12), 840-848, 2013
1372013
Natural killer cells in myeloid malignancies: immune surveillance, NK cell dysfunction, and pharmacological opportunities to bolster the endogenous NK cells
M Carlsten, M Järås
Frontiers in immunology 10, 489241, 2019
1362019
Selective killing of candidate AML stem cells by antibody targeting of IL1RAP
M Askmyr, H Ågerstam, N Hansen, S Gordon, A Arvanitakis, M Rissler, ...
Blood, The Journal of the American Society of Hematology 121 (18), 3709-3713, 2013
1352013
Antibodies targeting human IL1RAP (IL1R3) show therapeutic effects in xenograft models of acute myeloid leukemia
H Ågerstam, C Karlsson, N Hansen, C Sandén, M Askmyr, S von Palffy, ...
Proceedings of the National Academy of Sciences 112 (34), 10786-10791, 2015
1272015
IL1RAP antibodies block IL-1–induced expansion of candidate CML stem cells and mediate cell killing in xenograft models
H Ågerstam, N Hansen, S von Palffy, C Sandén, K Reckzeh, C Karlsson, ...
Blood, The Journal of the American Society of Hematology 128 (23), 2683-2693, 2016
1042016
Csnk1a1 inhibition has p53-dependent therapeutic efficacy in acute myeloid leukemia
M Järås, PG Miller, LP Chu, RV Puram, EC Fink, RK Schneider, ...
Journal of Experimental Medicine 211 (4), 605-612, 2014
1032014
Functional screen of MSI2 interactors identifies an essential role for SYNCRIP in myeloid leukemia stem cells
LP Vu, C Prieto, EM Amin, S Chhangawala, A Krivtsov, MN Calvo-Vidal, ...
Nature genetics 49 (6), 866-875, 2017
872017
In-depth genetic analysis of sclerosing epithelioid fibrosarcoma reveals recurrent genomic alterations and potential treatment targets
E Arbajian, F Puls, CR Antonescu, F Amary, R Sciot, M Debiec-Rychter, ...
Clinical Cancer Research 23 (23), 7426-7434, 2017
782017
CD36 defines primitive chronic myeloid leukemia cells less responsive to imatinib but vulnerable to antibody-based therapeutic targeting
N Landberg, S von Palffy, M Askmyr, H Lilljebjörn, C Sandén, M Rissler, ...
haematologica 103 (3), 447, 2018
542018
Functionally distinct subpopulations of cord blood CD34+ cells are transduced by adenoviral vectors with serotype 5 or 35 tropism
M Nilsson, S Karlsson, X Fan
Molecular Therapy 9 (3), 377-388, 2004
532004
IL1RAP expression as a measure of leukemic stem cell burden at diagnosis of chronic myeloid leukemia predicts therapy outcome
N Landberg, N Hansen, M Askmyr, H Ågerstam, C Lassen, M Rissler, ...
Leukemia 30 (1), 255-258, 2016
502016
De novo activating mutations drive clonal evolution and enhance clonal fitness in KMT2A-rearranged leukemia
A Hyrenius-Wittsten, M Pilheden, H Sturesson, J Hansson, MP Walsh, ...
Nature Communications 9 (1), 1770, 2018
452018
Interleukin 4 induces apoptosis of acute myeloid leukemia cells in a Stat6-dependent manner
P Peña-Martínez, M Eriksson, R Ramakrishnan, M Chapellier, C Högberg, ...
Leukemia 32 (3), 588-596, 2018
442018
Agonistic targeting of TLR1/TLR2 induces p38 MAPK-dependent apoptosis and NFκB-dependent differentiation of AML cells
M Eriksson, P Peña-Martínez, R Ramakrishnan, M Chapellier, C Högberg, ...
Blood advances 1 (23), 2046-2057, 2017
422017
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