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Zhi Z. Geng
Zhi Z. Geng
Postdoctoral Scholar, Pritzker School of Molecular Enigneering, the University of Chicago
在 uchicago.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
A quick route to multiple highly potent SARS‐CoV‐2 main protease inhibitors
KS Yang, XR Ma, Y Ma, YR Alugubelli, DA Scott, EC Vatansever, ...
ChemMedChem 16 (6), 942-948, 2021
1072021
Epoxides as alkylating reagents for the Catellani reaction
HG Cheng, C Wu, H Chen, R Chen, G Qian, Z Geng, Q Wei, Y Xia, ...
Angewandte Chemie International Edition 57 (13), 3444-3448, 2018
892018
Convergent syntheses of 2, 3-dihydrobenzofurans via a Catellani strategy
C Wu, HG Cheng, R Chen, H Chen, ZS Liu, J Zhang, Y Zhang, Y Zhu, ...
Organic Chemistry Frontiers 5 (17), 2533-2536, 2018
442018
Evaluation of SARS-CoV-2 main protease inhibitors using a novel cell-based assay
W Cao, CCD Cho, ZZ Geng, N Shaabani, XR Ma, EC Vatansever, ...
ACS central science 8 (2), 192-204, 2022
382022
A multi-pronged evaluation of aldehyde-based tripeptidyl main protease inhibitors as SARS-CoV-2 antivirals
Y Ma, KS Yang, ZZ Geng, YR Alugubelli, N Shaabani, EC Vatansever, ...
European Journal of Medicinal Chemistry 240, 114570, 2022
342022
A systematic exploration of boceprevir-based main protease inhibitors as SARS-CoV-2 antivirals
YR Alugubelli, ZZ Geng, KS Yang, N Shaabani, K Khatua, XR Ma, ...
European Journal of Medicinal Chemistry 240, 114596, 2022
292022
A reversible chemogenetic switch for chimeric antigen receptor T cells
W Cao, ZZ Geng, N Wang, Q Pan, S Guo, S Xu, J Zhou, WR Liu
Angewandte Chemie 134 (10), e202109550, 2022
142022
A systematic survey of reversibly covalent dipeptidyl inhibitors of the SARS-CoV-2 main protease
ZZ Geng, S Atla, N Shaabani, V Vulupala, KS Yang, YR Alugubelli, ...
Journal of medicinal chemistry 66 (16), 11040-11055, 2023
102023
Repurposing Halicin as a potent covalent inhibitor for the SARS-CoV-2 main protease
KS Yang, STA Kuo, LR Blankenship, ZZ Geng, SG Li, DH Russell, X Yan, ...
Current Research in Chemical Biology 2, 100025, 2022
92022
A designed, highly efficient pyrrolysyl-tRNA synthetase mutant binds o-chlorophenylalanine using two halogen bonds
EC Vatansever, KS Yang, ZZ Geng, Y Qiao, P Li, S Xu, WR Liu
Journal of molecular biology 434 (8), 167534, 2022
72022
Cellular activities of SARS-CoV-2 main protease inhibitors reveal their unique characteristics
W Cao, CCD Cho, ZZ Geng, XR Ma, R Allen, N Shaabani, EC Vatansever, ...
bioRxiv, 2021.06. 08.447613, 2021
72021
The N-Terminal Carbamate is Key to High Cellular and Antiviral Potency for Boceprevir-Based SARS-CoV-2 Main Protease Inhibitors
YR Alugubelli, ZZ Geng, KS Yang, N Shaabani, K Khatua, XR Ma, ...
BioRxiv, 2021.12. 18.473330, 2021
52021
The P3 O-Tert-Butyl-Threonine is Key to High Cellular and Antiviral Potency for Aldehyde-Based SARS-CoV-2 Main Protease Inhibitors
Y Ma, KS Yang, ZZ Geng, YR Alugubelli, N Shaabani, EC Vatansever, ...
bioRxiv, 2021.12. 18.473326, 2021
42021
Leveraging a Phage-Encoded Noncanonical Amino Acid: A Novel Pathway to Potent and Selective Epigenetic Reader Protein Inhibitors
PHC Chen, XS Guo, HE Zhang, GK Dubey, ZZ Geng, CA Fierke, S Xu, ...
ACS Central Science 10 (4), 782-792, 2024
22024
An amber-encoding helper phage for more efficient phage display of noncanonical amino acids
JT Hampton, CCD Cho, DD Coleman, ZZ Geng, PHC Chen, GK Dubey, ...
Nucleic Acids Research 51 (13), 6566-6577, 2023
22023
Azapeptides with unique covalent warheads as SARS-CoV-2 main protease inhibitors
K Khatua, YR Alugubelli, KS Yang, VR Vulupala, LR Blankenship, ...
Antiviral Research 225, 105874, 2024
12024
An Azapeptide Platform in Conjunction with Covalent Warheads to Uncover High-Potency Inhibitors for SARS-CoV-2 Main Protease
K Khatua, YR Alugubelli, KS Yang, VR Vulupala, LR Blankenship, ...
bioRxiv, 2023.04. 11.536467, 2023
12023
Phage-Assisted, Active Site-Directed Ligand Evolution with a Genetically Encoded Nε-Butyryl-L-Lysine to Identify a Cellularly Potent and Selective Inhibitor for …
PHC Chen, XS Guo, HE Zhang, ZZ Geng, GK Dubey, CA Fierke, S Xu, ...
bioRxiv, 2023.01. 08.523168, 2023
2023
Titelbild: A Reversible Chemogenetic Switch for Chimeric Antigen Receptor T Cells (Angew. Chem. 10/2022)
W Cao, ZZ Geng, N Wang, Q Pan, S Guo, S Xu, J Zhou, WR Liu
Angewandte Chemie 134 (10), e202201860, 2022
2022
Cover Picture: A Reversible Chemogenetic Switch for Chimeric Antigen Receptor T Cells (Angew. Chem. Int. Ed. 10/2022)
W Cao, ZZ Geng, N Wang, Q Pan, S Guo, S Xu, J Zhou, WR Liu
Angewandte Chemie International Edition 61 (10), e202201860, 2022
2022
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