Small molecule inhibitors reveal Niemann–Pick C1 is essential for Ebola virus infection M Côté, J Misasi, T Ren, A Bruchez, K Lee, CM Filone, L Hensley, Q Li, ... Nature 477 (7364), 344-348, 2011 | 819 | 2011 |
Protective monotherapy against lethal Ebola virus infection by a potently neutralizing antibody D Corti, J Misasi, S Mulangu, DA Stanley, M Kanekiyo, S Wollen, ... Science 351 (6279), 1339-1342, 2016 | 409 | 2016 |
SARS-CoV-2 Omicron variant neutralization after mRNA-1273 booster vaccination R Pajon, NA Doria-Rose, X Shen, SD Schmidt, S O’Dell, C McDanal, ... New England Journal of Medicine 386 (11), 1088-1091, 2022 | 366 | 2022 |
LY-CoV1404 (bebtelovimab) potently neutralizes SARS-CoV-2 variants K Westendorf, S Žentelis, L Wang, D Foster, P Vaillancourt, M Wiggin, ... Cell reports 39 (7), 2022 | 365 | 2022 |
Structural and molecular basis for Ebola virus neutralization by protective human antibodies J Misasi, MSA Gilman, M Kanekiyo, M Gui, A Cagigi, S Mulangu, D Corti, ... Science 351 (6279), 1343-1346, 2016 | 200 | 2016 |
Ultrapotent antibodies against diverse and highly transmissible SARS-CoV-2 variants L Wang, T Zhou, Y Zhang, ES Yang, CA Schramm, W Shi, A Pegu, ... Science 373 (6556), eabh1766, 2021 | 193 | 2021 |
Nucleic acid arrays and methods of synthesis CR Sabanayagam, T Sano, J Misasi, A Hatch, C Cantor US Patent 6,284,497, 2001 | 175 | 2001 |
Safety, tolerability, pharmacokinetics, and immunogenicity of the therapeutic monoclonal antibody mAb114 targeting Ebola virus glycoprotein (VRC 608): an open-label phase 1 study MR Gaudinski, EE Coates, L Novik, A Widge, KV Houser, E Burch, ... The Lancet 393 (10174), 889-898, 2019 | 135 | 2019 |
Filoviruses require endosomal cysteine proteases for entry but exhibit distinct protease preferences J Misasi, K Chandran, JY Yang, B Considine, CM Filone, M Côté, ... Journal of virology 86 (6), 3284-3292, 2012 | 134 | 2012 |
Structural basis for potent antibody neutralization of SARS-CoV-2 variants including B. 1.1. 529 T Zhou, L Wang, J Misasi, A Pegu, Y Zhang, DR Harris, AS Olia, ... Science 376 (6591), eabn8897, 2022 | 129 | 2022 |
Functional interrogation and mining of natively paired human VH:VL antibody repertoires B Wang, BJ DeKosky, MR Timm, J Lee, E Normandin, J Misasi, R Kong, ... Nature biotechnology 36 (2), 152-155, 2018 | 128 | 2018 |
Camouflage and misdirection: the full-on assault of ebola virus disease J Misasi, NJ Sullivan Cell 159 (3), 477-486, 2014 | 104 | 2014 |
Protection against SARS-CoV-2 Beta variant in mRNA-1273 vaccine–boosted nonhuman primates KS Corbett, M Gagne, DA Wagner, S O’Connell, SR Narpala, DR Flebbe, ... Science 374 (6573), 1343-1353, 2021 | 91 | 2021 |
Rolling circle amplification of DNA immobilized on solid surfaces and its application to multiplex mutation detection A Hatch, T Sano, J Misasi, CL Smith Genetic analysis: biomolecular engineering 15 (2), 35-40, 1999 | 89 | 1999 |
Booster of mRNA-1273 strengthens SARS-CoV-2 Omicron neutralization NA Doria-Rose, X Shen, SD Schmidt, S O’Dell, C McDanal, W Feng, ... MedRxiv, 2021 | 87 | 2021 |
Ebola virus transmission initiated by relapse of systemic Ebola virus disease P Mbala-Kingebeni, C Pratt, M Mutafali-Ruffin, MG Pauthner, F Bile, ... New England Journal of Medicine 384 (13), 1240-1247, 2021 | 84 | 2021 |
Eastern equine encephalitis in children, Massachusetts and New Hampshire, USA, 1970–2010 MA Silverman, J Misasi, S Smole, HA Feldman, AB Cohen, S Santagata, ... Emerging infectious diseases 19 (2), 194, 2013 | 76 | 2013 |
Ebolavirus Δ-peptide immunoadhesins inhibit Marburgvirus and Ebolavirus cell entry SR Radoshitzky, KL Warfield, X Chi, L Dong, K Kota, SB Bradfute, ... Journal of virology 85 (17), 8502-8513, 2011 | 69 | 2011 |
Booster of mRNA-1273 vaccine reduces SARS-CoV-2 Omicron escape from neutralizing antibodies NA Doria-Rose, X Shen, SD Schmidt, S O’Dell, C McDanal, W Feng, ... MedRxiv, 2021 | 64 | 2021 |
Structure-based design with tag-based purification and in-process biotinylation enable streamlined development of SARS-CoV-2 spike molecular probes T Zhou, IT Teng, AS Olia, G Cerutti, J Gorman, A Nazzari, W Shi, ... Cell reports 33 (4), 2020 | 62 | 2020 |